Home Failed Back Surgery Treatment
Cell Star

Understanding Failed Back Surgery Syndrome (FBSS)

Failed Back Surgery Syndrome (FBSS) refers to persistent or recurrent pain following spinal surgery. Despite undergoing procedures aimed at relieving back or leg pain—such as discectomy, laminectomy, or spinal fusion—some patients continue to experience significant discomfort or even worsening of symptoms.

FBSS is not a specific disease, but a generalized term describing the unsatisfactory outcome of spinal surgery. It is a complex condition influenced by anatomical, surgical, and psychological factors.

Symptoms of FBSS

Common symptoms associated with FBSS include:

  • Persistent low back paind of the day
  • Radiating leg pain (sciatica)
  • Numbness or tingling in the legs
  • Limited mobility or stiffness in the back
  • Pain that worsens with movement or prolonged sitting
  • Depression or anxiety due to chronic pain

Causes and Risk Factors

Several factors can contribute to the development of FBSS:

  • Incomplete or incorrect diagnosis before surgery
  • Inappropriate choice of surgical procedure
  • Scar tissue formation (epidural fibrosis) near nerve roots
  • Recurrent or residual disc herniation
  • Spinal instability or adjacent segment degeneration
  • Psychological factors such as stress or depression
  • Poor rehabilitation or post-operative care

Conventional Treatment Approaches

Managing FBSS can be challenging and often requires a multidisciplinary approach. Conventional treatments may include:

  • Physical therapy and rehabilitation
  • Non-steroidal anti-inflammatory drugs (NSAIDs)
  • Neuropathic pain medications (e.g., gabapentin, pregabalin)
  • Epidural steroid injections
  • Nerve blocks or radiofrequency ablation
  • Spinal cord stimulation (SCS)
  • Psychological counseling or cognitive behavioral therapy
  • Revision spine surgery in selected cases

These treatments aim to manage symptoms rather than address the root cause of persistent pain. In many cases, pain relief remains limited.

Stem Cell Research in FBSS – A Regenerative Possibility

As traditional approaches may fail to deliver lasting relief for FBSS, scientists and clinicians are exploring regenerative options. Among the most promising is the use of mesenchymal stem cells (MSCs) in spinal health research.

What Are Mesenchymal Stem Cells (MSCs)?

MSCs are multipotent adult stem cells found in bone marrow, adipose tissue, and other sources. They possess:

  • Anti-inflammatory and immunomodulatory properties
  •  The ability to release growth factors that support tissue repair
  • Potential to differentiate into nerve, bone, and cartilage cells

How Stem Cells May Help in FBSS

The investigational role of MSCs in FBSS focuses on several key mechanisms:

  • Reducing epidural scar tissue that compresses nerves
  • Modulating inflammation in the damaged spinal environment
  • Supporting nerve healing and remyelination
  • Promoting recovery of surrounding soft tissues

By creating a more favorable healing environment, stem cells may help reduce chronic pain and improve mobility.

Current Research and Limitations

At present, stem cell use in FBSS is only available within approved clinical research settings.

CellStar’s Role in FBSS Awareness

CellStar does not provide direct stem cell treatment. Our mission is to:

  • Educate the public and healthcare professionals about investigational therapies
  • Share emerging research findings and ongoing research
  • Promote ethical and evidence-based exploration of regenerative medicine

Conclusion

Failed Back Surgery Syndrome is a debilitating condition that can deeply affect a person’s quality of life. With traditional treatments often falling short, the promise of stem cell research provides a ray of hope. While still investigational, stem cells may offer new ways to address chronic spinal pain in the future.

Patients are encouraged to stay informed, consult healthcare professionals, and approach regenerative solutions with scientific awareness. For credible information and updates on spinal regenerative research, CellStar remains your trusted knowledge partner.

Working Time
  • Monday-Saturday 09:00 AM  TO 06:00 PM
Contact Info